Kev laus yog ib qho teeb meem uas txhua leej txhua tus yuav tsum tau ntsib, thiab cov kws tshawb fawb ntseeg tias kev laus yog ib qho kev puas tsuaj zuj zus ntawm cov qib cellular thiab molecular. Tshwj xeeb, nws suav nrog oxidative kev nyuaj siab (dawb radicals tua hlwb), telomere depletion (lub hau tiv thaiv thaum kawg ntawm chromosome ua luv), mob qis- qib o, thiab lwm yam. Cov kev hloov kho microscopic no yuav ua rau muaj kev pheej hmoo ntawm cov kab mob ntev xws li ntshav qab zib, kab mob plawv thiab kab mob cerebrovascular, thiab Alzheimer.
Haus 6-8 grams tshuaj yej ib hnub twg tuaj yeem ncua kev laus ntawm lub cev
Raws li ib txwm haus dej haus nyob rau sab hnub tuaj, tshuaj yej cov ntsiab lus tseem ceeb tau raug pov thawj los cuam tshuam hauv cov txheej txheem kev laus los ntawm ntau yam - lub hom phiaj thiab ntau txoj hauv kev sib koom ua ke, dhau los ua ib qho kev cuam tshuam rau kev noj qab haus huv.
Cov tshuaj nquag hauv tshuaj yej, xws li tshuaj yej polyphenols, theanine, tshuaj yej pigments, thiab tshuaj yej polysaccharides, tuaj yeem tsim cov txheej txheem tswj hwm hauv ntau qhov ntev, suav nrog kev ua haujlwm antioxidant, kev tswj cov piam thaj thiab lipid metabolism, txhim kho vascular endothelial muaj nuj nqi, txhim kho kev tiv thaiv kab mob, sib npaug ntawm plab hnyuv microbiotatic, thiab Qhov no muab ib qho kev daws teeb meem rau kev ncua kev laus hauv lub cev.
Kev tshawb fawb tau pom tias haus 6-8 grams tshuaj yej ib hnub twg tuaj yeem ncua kev laus hauv lub cev. Piv nrog cov neeg tsis haus tshuaj yej, cov neeg haus tshuaj yej muaj qhov hloov pauv DNA methylation moos thiab txhim kho qib ntawm cov laus muaj feem xyuam nrog biomarkers.
Qhov teeb meem no tshuaj xyuas cov tshuaj nquag hauv tshuaj yej, xws li tshuaj yej polyphenols, theanine, tshuaj yej pigments, thiab tshuaj yej polysaccharides, uas synergistically ncua tib neeg kev laus mechanisms los ntawm ntau yam - lub hom phiaj thiab ntau txoj hauv kev.
Cov tshuaj tiv thaiv -aging nyhuv ntawm tshuaj yej polyphenols
Cov txiaj ntsig tseem ceeb ntawm cov tshuaj yej polyphenols nyob hauv lawv cov tshuaj tiv thaiv kab mob antioxidant thiab dawb radical scavenging peev xwm. Nws lub ntsiab mechanisms muaj xws li:
Kev tswj cov txheej txheem oxidoreductase: Tshuaj yej polyphenols tuaj yeem ua rau muaj kev tswj hwm ntawm oxidoreductase system, txhim kho lub cev tus kheej cov tshuaj tiv thaiv antioxidant.
Tshem tawm cov dawb radicals: Tshuaj yej polyphenols (nrog EGCG ua lub hauv paus) tso siab rau lawv cov phenolic hydroxyl qauv kom ncaj qha tshem tawm cov dawb radicals, thaum ua kom cov Nrf2 antioxidant txoj kev thiab inhibiting NF kB inflammatory pathway. Lawv tau pom tias muaj kev cuam tshuam hauv kev ncua kev laus thiab txhim kho cov kab mob metabolic hauv cov cellular thiab tsiaj cov qauv.
Inhibit oxidase kev ua, chelate hloov pauv hlau ions xws li hlau thiab tooj liab, thiab txo lawv cov catalytic dawb radical tiam.
Antiviral effect: Tshuaj yej polyphenols muaj kev cuam tshuam rau ntau yam kab mob xws li kab mob khaub thuas, kab mob ua pa, enterovirus, thiab txawm tias HIV.
Tiv thaiv cov hlab ntsha: Tshuaj yej polyphenols tuaj yeem tiv thaiv lub paj hlwb, tiv thaiv cov kab mob hauv lub paj hlwb, thiab kho kev puas siab puas ntsws los ntawm kev laus lossis lwm yam kab mob neurological.
Cov tshuaj tiv thaiv- kev laus ntawm theanine
Theanine tuaj yeem ntes cov reactive carbonyl tebchaw, txhim khu kev ua haujlwm ntawm cov enzymes antioxidant xws li SOD (superoxide dismutase) thiab CAT (catalase), inhibit inflammatory cascade reactions, thiab nthuav tawm ntau cov ntaub so ntswg tiv thaiv hauv neuroprotection, skeletal leeg tiv thaiv - laus, thiab qog qauv.
L-theanine yog cov yam ntxwv uas tsis yog protein amino acid muaj nyob rau hauv cov tshuaj yej nplooj, nrog cov qauv tshuaj zoo ib yam li glutamic acid. Cov tshuaj no nthuav tawm ntau yam kev ua ub no, suav nrog kev tiv thaiv kab mob thiab tiv thaiv kev laus -.
Nkag mus rau hauv cov ntshav- lub hlwb teeb meem: Nws tuaj yeem nkag mus rau hauv nruab nrab lub paj hlwb, tswj cov qib neurotransmitter, thiab txhawb kev txhim kho hauv kev txawj ntse.
Ntau yam teebmeem ntawm lub cev: antioxidant, tiv thaiv - mob, tiv thaiv lub paj hlwb, tswj kev tiv thaiv kab mob, tiv thaiv- mob qog noj ntshav, txo qis kev pheej hmoo ntawm cov hlab plawv, txo cov cawv ua rau lub siab puas tsuaj, thiab lwm yam.
Kev ncua kev laus: nthuav tawm kev tiv thaiv kab mob thiab ncua kev cuam tshuam
Ntau yam kev ua ub no suav nrog kev laus.
Cov tshuaj tiv thaiv -aging nyhuv ntawm tshuaj yej pigments
Tshuaj yej pigment yog cov yam ntxwv cog phenolic pigment tsim los ntawm catalytic oxidation thiab polymerization ntawm polyphenolic tshuaj nyob rau hauv tshuaj yej nplooj los ntawm ib tug endogenous enzyme system. Nws biosynthesis yog cov txheej txheem biochemical tseem ceeb hauv kev ua tshuaj yej: kev poob dej thaum lub caij nplooj ntoos zeeg ntawm cov tshuaj yej nplooj ua rau poob ntawm cell turgor siab, uas ua rau muaj kev ua haujlwm ntawm endogenous oxidases xws li polyphenol oxidase thiab peroxidase. Kwv yees li 75% ntawm cov tshuaj yej pigments nyob rau hauv tshuaj yej yog catalyzed los ntawm no enzyme system. Cov txheej txheem no siv quinone ua qhov tseem ceeb ua ntej thiab dhau los ua cov tshuaj tiv thaiv cascade polymerization rau thaum kawg tsim peb yam tseem ceeb: theaflavins, thearubigins, thiab theaflavins.
Theaflavins thiab theaflavins tuaj yeem tsis tsuas yog siv cov tshuaj antioxidant ncaj qha los ntawm chelating hlau ions thiab tswj cov kab mob redox, tab sis kuj tswj cov plab hnyuv microbiota thiab thaiv daim tawv nqaij photoaging, tsim kev tiv thaiv - hom kev laus uas sib npaug rau sab hauv thiab sab nraud.
Cov tshuaj tiv thaiv - kev laus ntawm cov tshuaj yej xim yog ua raws li cov txheej txheem tseem ceeb ntawm antioxidant thiab tiv thaiv - cov teebmeem inflammatory, uas ua haujlwm sib koom ua ke los ntawm lub cev chelation thiab txoj kev tswj hwm los tiv thaiv biofilms thiab thaiv cov lus teb inflammatory, muab kev tiv thaiv ntau yam rau lub cev tiv thaiv kev laus.
Cov tshuaj tiv thaiv -aging nyhuv ntawm tshuaj yej polysaccharides
Tshuaj yej polysaccharides yog siab molecular hnyav acidic glycoproteins nyob rau hauv tshuaj yej uas yog covalently khi los ntawm monosaccharides thiab proteins, thiab feem ntau muaj ib tug tej yam nyiaj txiag ions. Lawv crude extracts muaj kev ua haujlwm zoo dua li cov khoom purified. Lawv tsim muaj kev sib koom ua ke los tiv thaiv kev laus los ntawm peb lub tswv yim: tswj kev tiv thaiv kab mob, tswj cov piam thaj thiab lipid metabolism hauv homeostasis, thiab ntxiv dag zog rau kev tiv thaiv kab mob antioxidant.
Kev ua haujlwm antioxidant ntawm tshuaj yej polysaccharides tau dav siv tau hauv ntau hom tsiaj:
Hauv ntau hom tsiaj xws li tib neeg, nas, thiab nqaij qaib, tshuaj yej polysaccharides tuaj yeem txo cov cellular oxidative kev nyuaj siab los ntawm kev tshem tawm cov dawb radicals ncaj qha thiab tswj kev ua haujlwm ntawm cov enzyme antioxidant.
Nws tuaj yeem hais meej meej superoxide thiab hydroxyl radicals, inhibit qhov tsub zuj zuj ntawm oxidative khoom xws li ROS (reactive oxygen hom) thiab MDA (malondialdehyde) hauv hlwb.
Ib txhij txhawb kev ua haujlwm ntawm cov enzymes tseem ceeb antioxidant xws li SOD thiab CAT.
Xaus
Cov kev tshawb fawb uas twb muaj lawm tau pom tias cov khoom xyaw nquag xws li tshuaj yej polyphenols, theanine, tshuaj yej pigments, thiab tshuaj yej polysaccharides hauv tshuaj yej tuaj yeem cuam tshuam kev laus los ntawm ntau txoj hauv kev, thiab plaub yam tseem ceeb kuj muaj kev sib koom ua ke. Piv txwv li, theanine thiab EGCG℃txhim kho antioxidant muaj peev xwm los ntawm kev sib txuas ntawm cov hydrogen sib txuas, thiab tsis tshua muaj cov tshuaj yej polyphenols thiab tshuaj yej polysaccharides ntxiv rau ib leeg hauv qee yam mob. Qhov no muab cov tswv yim tshiab rau kev txhim kho ntuj thiab nyab xeeb los tiv thaiv- cov tswv yim cuam tshuam kev laus, tab sis kev soj ntsuam kev soj ntsuam tseem xav tau los qhia kom meej ntev - cov txiaj ntsig thiab kev noj kom zoo.
